Topic outline
Main course page
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Lecturer in charge: Dr. Gan Sook Yee
Average minutes to complete this topic: 120 minutes and Case Discussion – 360 minutes
Advances in human genome research are opening the door to a new paradigm for practising medicine that promises to transform healthcare. Personalised medicine, the use of marker-assisted diagnosis and targeted therapies derived from an individual's molecular profile, will impact the way drugs are developed and medicine is practiced.
But how far have we come, and how close is personalised medicine in delivering its promise? This series of lectures will explore the promises and challenges in personalized medicine, and its implication to the social-economy of the society. The lectures will also discuss the importance of various biomarkers and the emerging technology in diagnostic medicine.
At the end of the lecture, student will be given a case discussion, where they are required to perform critical analysis and conduct an open discussion with the class.
At the end of these activities, you should be able to understand the promises and challenges in personalised medicine and to integrate molecular and cellular biology in relation to human diseases and treatment.
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Learning Resources in Topic 1:
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In this section, we will first define the term genomic, followed by explaining the application of genomic profiles.
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In this section, we will discuss the difference between low throughput high accuracy methods and high throughput low accuracy method. We will also visualise the problems that we will face when dealing with omic data.
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In this section we will talk about the objectives of human genome project
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This video will give you a brief description of the history of human genome project
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In this section we will talk about big data. We will also briefly explain the databases available to download genomic data and the methods to analyse them.
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This video explain the power of big data and the danger when your big data are being used against your interest.
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Knowledge Check Activities:
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