| Section | Name | Description |
|---|---|---|
| Module Introduction | ||
. |
||
Area of expertise: Molecular Biology, Pharmacogenomics Dr Hazwanie received her Ph.D. in Pharmacogenomics at the Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam based on her study title, "Integrated pharmacogenomics - metabolomics approaches in personalising medicine for colorectal cancer treated with 5-fluorouracil." Integration of pharmacogenomics and metabolomics in personalising medicine intended to profile both the genetics and metabolomics markers that could be useful in the clinical monitoring of patients’ responses towards 5-FU and its disease.
She and her research team has received international and local awards for their research findings. Her research interest is on the role of genome variations towards precision medicine in obesity and metabolic disorders. |
||
| Assessment | Dear students, Please view this recorded video to learn more on assessment and requirement for this module. |
|
| Topic 1: | In this section, we will first define the term genomic, followed by explaining the application of genomic profiles. |
|
In this section, we will discuss the difference between low throughput high accuracy methods and high throughput low accuracy method. We will also visualise the problems that we will face when dealing with omic data. |
||
In this section we will talk about the objectives of human genome project |
||
This video will give you a brief description of the history of human genome project |
||
In this section we will talk about big data. We will also briefly explain the databases available to download genomic data and the methods to analyse them. |
||
This video explain the power of big data and the danger when your big data are being used against your interest. |
||
| Topic 2: | The central dogma of molecular biology refers to the processes of gene expression. Each step of gene expression corresponds with a type of omic. For example, transcription corresponds with transcriptomic while translation corresponds to proteomic etc. In this section, we will briefly explain the processes of gene expression. |
|
Genetic variation and environmental factors lead to the diversity that we observe in each individual. In this section we will discuss about normal genetic variation that leads to normal phenotypic diversity and rare genetic variation that leads to diseases. |
Background Colour
Font Face
Font Size
Text Colour