Section: Topic 2: Bacterial pathogenesis | MM302 Immunology and Infection (Trial) | IMU ODL

    • In this topic, a recent example of the latest emerging/re-emerging bacterial pathogen is used as a model for discussion on bacterial pathogenesis e.g. Mycobacterium tuberculosis. The learning issues will include mechanisms in bacterial infection and pathogenesis, virulence factors, antigenic targets, resistance and current or experimental therapies. Please note that your participation in the knowledge check activity will be used as your attendance. 


    • Learning Outcomes

    • Upon completion of this topic, students should be able to: 

      1. describe the mechanism of bacterial pathogenesis. 

      2. describe the immune response agains bacterial infection. 


    • Learning Materials

    • Emerging and re-emerging diseases are arise due to many reason. Re-emerging disease may arise due to incomplete vaccination in a population, over usage of antibiotics and many other reasons. A few examples of emerging and re-emerging disease have been shown in this section. 

      We will use Mycobacterium tuberculosis as an example of reemerging disease for our discussion. This intracellular bacteria will cause tuberculosis which is increasing common in recent years. We will discuss about the bacteriology, epidemiology, primary infection, reactivation tuberculosis and the bacteria virulence machanism, 

      After that we will talk about the immune response that will be triggered by this bacteria, its clinical manifestation, diagnosis, treatment, potential treatment and prevention.

    • Learning Activities

    • Topic 2: Discussion: Reflective Writing
      Identify an emerging/re-emerging disease that is currently reported. Discuss about the pathogen, its virulence factors, antigenic targets, resistance and the current or experimental therapies designed for it. Please conduct the discussion via Microsoft Teams. 

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