Welcome students to Topic 2. The modes of learning for this topic is i-lecture and computer aided learning (CAL). In the CAL session, you will learn how to use structure based drug design tools in the Schrodinger Suite. You will then prepare a CAL report to suggest compounds with improved efficacy and safety against a given target. The CAL report will contribute to 10% of the module mark.
In this topic, you will learn the following lessons:
a. Theory and principles involved in structure based drug design
b. Preparation of receptor for molecular docking studies
c. Identification of binding sites
d. Rigid and induced fit docking
e. Interpretation and analysis of docking results
Please use firebox browser to view the i-lecture
2.1 Theory and principles involved in structure based drug design
2.2 Preparation of receptor for molecular docking studies
